\u03a4\u03b1 \u03b5\u03bc\u03b2\u03cc\u03bb\u03b9\u03b1 \u03ad\u03bd\u03b1\u03bd\u03c4\u03b9 \u03c4\u03b7\u03c2 COVID-19 \u03c0\u03bf\u03c5 \u03b2\u03b1\u03c3\u03af\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c3\u03c4\u03b7 \u03bd\u03ad\u03b1 \u03c4\u03b5\u03c7\u03bd\u03bf\u03bb\u03bf\u03b3\u03af\u03b1 mRNA \u03b1\u03c0\u03bf\u03b4\u03b5\u03b9\u03ba\u03bd\u03cd\u03bf\u03bd\u03c4\u03b1\u03b9 \u03b1\u03c3\u03c6\u03b1\u03bb\u03ae \u03ba\u03b1\u03b9 \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03b5\u03c3\u03bc\u03b1\u03c4\u03b9\u03ba\u03ac -\u03c3\u03b5 \u03c0\u03bf\u03bb\u03cd \u03bc\u03b5\u03b3\u03ac\u03bb\u03bf \u03b2\u03b1\u03b8\u03bc\u03cc- \u03c3\u03c4\u03b7\u03bd \u03b1\u03c0\u03bf\u03c4\u03c1\u03bf\u03c0\u03ae \u03bd\u03bf\u03c3\u03b7\u03bb\u03b5\u03b9\u03ce\u03bd \u03ba\u03b1\u03b9 \u03b8\u03b1\u03bd\u03ac\u03c4\u03c9\u03bd \u03b1\u03c0\u03cc \u03c4\u03b7 \u03bd\u03cc\u03c3\u03bf. \u039a\u03b1\u03b8\u03ce\u03c2 \u03bf \u03bc\u03b1\u03b6\u03b9\u03ba\u03cc\u03c2 \u03b5\u03bc\u03b2\u03bf\u03bb\u03b9\u03b1\u03c3\u03bc\u03cc\u03c2 \u03c3\u03c5\u03bd\u03b5\u03c7\u03af\u03b6\u03b5\u03c4\u03b1\u03b9, \u03bc\u03ad\u03c3\u03b1 \u03b1\u03c0\u03cc \u03c4\u03b1 \u03c0\u03c1\u03c9\u03c4\u03cc\u03ba\u03bf\u03bb\u03bb\u03b1 \u03c6\u03b1\u03c1\u03bc\u03b1\u03ba\u03bf\u03b5\u03c0\u03b1\u03b3\u03c1\u03cd\u03c0\u03bd\u03b7\u03c3\u03b7\u03c2 \u03c0\u03b1\u03c1\u03b1\u03c4\u03b7\u03c1\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9 \u03ba\u03b1\u03b9 \u03ba\u03b1\u03c4\u03b1\u03b3\u03c1\u03ac\u03c6\u03bf\u03bd\u03c4\u03b1\u03b9 \u03cc\u03bb\u03b1 \u03cc\u03c3\u03b1 \u03b1\u03c6\u03bf\u03c1\u03bf\u03cd\u03bd \u03c4\u03b7\u03bd \u03b1\u03c3\u03c6\u03ac\u03bb\u03b5\u03b9\u03b1 \u03c4\u03c9\u03bd \u03b5\u03bc\u03b2\u03bf\u03bb\u03af\u03c9\u03bd. \u03a3\u03b5 \u03b1\u03c5\u03c4\u03cc \u03c4\u03bf \u03c0\u03bb\u03b1\u03af\u03c3\u03b9\u03bf, \u03ba\u03ac\u03c0\u03bf\u03b9\u03b1 \u03b5\u03be\u03b1\u03b9\u03c1\u03b5\u03c4\u03b9\u03ba\u03ac \u03c3\u03c0\u03ac\u03bd\u03b9\u03b1 \u03c0\u03b5\u03c1\u03b9\u03c3\u03c4\u03b1\u03c4\u03b9\u03ba\u03ac \u03bc\u03c5\u03bf\u03ba\u03b1\u03c1\u03b4\u03af\u03c4\u03b9\u03b4\u03b1\u03c2 \u03ae \u03c0\u03b5\u03c1\u03b9\u03ba\u03b1\u03c1\u03b4\u03af\u03c4\u03b9\u03b4\u03b1\u03c2 (\u03b4\u03b7\u03bb\u03b1\u03b4\u03ae \u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03ae\u03c2 \u03c4\u03b7\u03c2 \u03ba\u03b1\u03c1\u03b4\u03b9\u03ac\u03c2 \u03ba\u03b1\u03b9 \u03c4\u03bf\u03c5 \u03c0\u03b5\u03c1\u03b9\u03ba\u03b1\u03c1\u03b4\u03af\u03bf\u03c5, \u03b1\u03bd\u03c4\u03af\u03c3\u03c4\u03bf\u03b9\u03c7\u03b1), \u03ae\u03c0\u03b9\u03b1 \u03c3\u03c4\u03b7\u03bd \u03c0\u03bb\u03b5\u03b9\u03bf\u03bd\u03cc\u03c4\u03b7\u03c4\u03ac \u03c4\u03bf\u03c5\u03c2, \u03c0\u03bf\u03c5 \u03ba\u03b1\u03c4\u03b1\u03b3\u03c1\u03ac\u03c6\u03b7\u03ba\u03b1\u03bd \u03b3\u03b9\u03b1 \u03c0\u03c1\u03ce\u03c4\u03b7 \u03c6\u03bf\u03c1\u03ac \u03c3\u03c4\u03bf \u0399\u03c3\u03c1\u03b1\u03ae\u03bb \u03c4\u03bf\u03bd \u0391\u03c0\u03c1\u03af\u03bb\u03b9\u03bf \u03c4\u03bf\u03c5 2021 \u03ba\u03b1\u03b9 \u03c3\u03c4\u03b7 \u03c3\u03c5\u03bd\u03ad\u03c7\u03b5\u03b9\u03b1 \u03c3\u03b5 \u03ac\u03bb\u03bb\u03b5\u03c2 \u03c7\u03ce\u03c1\u03b5\u03c2, \u03c3\u03c5\u03bd\u03b4\u03ad\u03b8\u03b7\u03ba\u03b1\u03bd \u03bc\u03b5 \u03c4\u03b7 \u03c7\u03bf\u03c1\u03ae\u03b3\u03b7\u03c3\u03b7 mRNA \u03b5\u03bc\u03b2\u03bf\u03bb\u03af\u03c9\u03bd. \u03a4\u03b9 \u03b1\u03ba\u03c1\u03b9\u03b2\u03ce\u03c2 \u03c3\u03c5\u03bd\u03ad\u03b2\u03b7; \u03a5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9 \u03c0\u03c1\u03ac\u03b3\u03bc\u03b1\u03c4\u03b9 \u03c3\u03c5\u03c3\u03c7\u03ad\u03c4\u03b9\u03c3\u03b7; \u03a4\u03b9 \u03c0\u03c1\u03bf\u03ba\u03b1\u03bb\u03b5\u03af \u03b1\u03c5\u03c4\u03ae\u03bd \u03c4\u03b7 \u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03ce\u03b4\u03b7 \u03b1\u03bd\u03c4\u03af\u03b4\u03c1\u03b1\u03c3\u03b7 \u03c3\u03c4\u03bf\u03bd \u03ba\u03b1\u03c1\u03b4\u03b9\u03b1\u03ba\u03cc \u03bc\u03c5\u03ca\u03ba\u03cc \u03b9\u03c3\u03c4\u03cc \u03bf\u03c1\u03b9\u03c3\u03bc\u03ad\u03bd\u03c9\u03bd \u03b1\u03c4\u03cc\u03bc\u03c9\u03bd;<\/p>\n\n\n\n
\u0397 \u03b1\u03c0\u03ac\u03bd\u03c4\u03b7\u03c3\u03b7, \u03cc\u03c0\u03c9\u03c2 \u03b1\u03bd\u03b1\u03c6\u03ad\u03c1\u03bf\u03c5\u03bd \u0388\u03bb\u03bb\u03b7\u03bd\u03b5\u03c2 \u03b5\u03c0\u03b9\u03c3\u03c4\u03ae\u03bc\u03bf\u03bd\u03b5\u03c2, \u03c0\u03b9\u03b8\u03b1\u03bd\u03cc\u03c4\u03b1\u03c4\u03b1 \u03b2\u03c1\u03af\u03c3\u03ba\u03b5\u03c4\u03b1\u03b9 \u03c3\u03c4\u03b7\u03bd \u03ba\u03b1\u03c1\u03b4\u03b9\u03ac \u03c4\u03b7\u03c2 \u03c4\u03b5\u03c7\u03bd\u03bf\u03bb\u03bf\u03b3\u03af\u03b1\u03c2 \u03c4\u03c9\u03bd \u03b5\u03bc\u03b2\u03bf\u03bb\u03af\u03c9\u03bd mRNA. \u03a3\u03cd\u03bc\u03c6\u03c9\u03bd\u03b1 \u03bc\u03b5 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b7 \u03c0\u03bf\u03c5 \u03b4\u03b7\u03bc\u03bf\u03c3\u03b9\u03b5\u03cd\u03b8\u03b7\u03ba\u03b5 \u03c3\u03c4\u03bf \u03ad\u03b3\u03ba\u03c5\u03c1\u03bf \u03b5\u03c0\u03b9\u03c3\u03c4\u03b7\u03bc\u03bf\u03bd\u03b9\u03ba\u03cc \u03c0\u03b5\u03c1\u03b9\u03bf\u03b4\u03b9\u03ba\u03cc Vaccine, \u03c0\u03b9\u03bf \u03c0\u03b9\u03b8\u03b1\u03bd\u03ae \u03b5\u03be\u03ae\u03b3\u03b7\u03c3\u03b7 \u03b5\u03af\u03bd\u03b1\u03b9 \u03cc\u03c4\u03b9 \u03b1\u03c5\u03c4\u03ad\u03c2 \u03bf\u03b9 \u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03ce\u03b4\u03b5\u03b9\u03c2 \u03b1\u03bd\u03c4\u03b9\u03b4\u03c1\u03ac\u03c3\u03b5\u03b9\u03c2 \u03c0\u03c1\u03bf\u03ba\u03b1\u03bb\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u03b1\u03bd\u03c4\u03af\u03b4\u03c1\u03b1\u03c3\u03b7 \u03b5\u03b3\u03b3\u03b5\u03bd\u03ce\u03bd \u03b1\u03bd\u03bf\u03c3\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ce\u03bd \u03b1\u03b9\u03c3\u03b8\u03b7\u03c4\u03ae\u03c1\u03c9\u03bd, \u03cc\u03c0\u03c9\u03c2 \u03b5\u03af\u03bd\u03b1\u03b9 \u03bf\u03b9 toll-like \u03c5\u03c0\u03bf\u03b4\u03bf\u03c7\u03b5\u03af\u03c2 (TLR3, TLR7, TLR8) \u03ba\u03b1\u03b9 \u03bf\u03b9 \u03ba\u03b9\u03bd\u03ac\u03c3\u03b5\u03c2 \u03ba\u03c5\u03c4\u03c4\u03b1\u03c1\u03bf\u03c0\u03bb\u03b1\u03c3\u03bc\u03b1\u03c4\u03b9\u03ba\u03ce\u03bd \u03c0\u03c1\u03c9\u03c4\u03b5\u03ca\u03bd\u03ce\u03bd (PKR, RIG-I, MDA5), \u03ad\u03bd\u03b1\u03bd\u03c4\u03b9 \u03ba\u03ac\u03c0\u03bf\u03b9\u03c9\u03bd \u03b5\u03c0\u03b9\u03c0\u03bb\u03ad\u03bf\u03bd \u03b5\u03b9\u03b4\u03ce\u03bd RNA (\u03bc\u03bf\u03bd\u03cc\u03ba\u03bb\u03c9\u03bd\u03bf\u03c5 \u03ba\u03b1\u03b9 \u03b4\u03af\u03ba\u03bb\u03c9\u03bd\u03bf\u03c5) \u03c0\u03bf\u03c5 \u03c0\u03b5\u03c1\u03b9\u03ad\u03c7\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c3\u03c4\u03b1 \u03b5\u03bc\u03b2\u03cc\u03bb\u03b9\u03b1 mRNA \u03ba\u03b1\u03b9 \u03b1\u03bd\u03b1\u03b3\u03bd\u03c9\u03c1\u03af\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03bf \u03b1\u03bd\u03bf\u03c3\u03bf\u03c0\u03bf\u03b9\u03b7\u03c4\u03b9\u03ba\u03cc \u03c3\u03cd\u03c3\u03c4\u03b7\u03bc\u03ac \u03bc\u03b1\u03c2 \u03c9\u03c2 \u03b4\u03c5\u03bd\u03ac\u03bc\u03b5\u03b9 \u03c0\u03b1\u03b8\u03bf\u03b3\u03cc\u03bd\u03bf\u03b9 \u00ab\u03b5\u03b9\u03c3\u03b2\u03bf\u03bb\u03b5\u03af\u03c2\u00bb (\u03b5\u03c0\u03b5\u03b9\u03b4\u03ae \u03c0\u03b1\u03c1\u03cc\u03bc\u03bf\u03b9\u03b1 \u03c4\u03bc\u03ae\u03bc\u03b1\u03c4\u03b1 \u03bd\u03bf\u03c5\u03ba\u03bb\u03b5\u03ca\u03ba\u03ce\u03bd \u03bf\u03be\u03ad\u03c9\u03bd \u03b8\u03b1 \u03bc\u03c0\u03bf\u03c1\u03bf\u03cd\u03c3\u03b1\u03bd \u03bd\u03b1 \u03b1\u03c0\u03b1\u03bd\u03c4\u03ce\u03bd\u03c4\u03b1\u03b9 \u03c3\u03b5 \u03c0\u03b1\u03b8\u03bf\u03b3\u03cc\u03bd\u03bf\u03c5\u03c2 \u03b9\u03bf\u03cd\u03c2).<\/p>\n\n\n\n
\u03a4\u03b1 \u03bc\u03cc\u03c1\u03b9\u03b1 RNA \u03c0\u03bf\u03c5 \u03b5\u03bd\u03b4\u03ad\u03c7\u03b5\u03c4\u03b1\u03b9 \u03bd\u03b1 \u03c0\u03c1\u03bf\u03ba\u03b1\u03bb\u03ad\u03c3\u03bf\u03c5\u03bd \u03c4\u03b7 \u03c3\u03c5\u03b3\u03ba\u03b5\u03ba\u03c1\u03b9\u03bc\u03ad\u03bd\u03b7 \u03b1\u03bd\u03bf\u03c3\u03bf\u03b4\u03b9\u03ad\u03b3\u03b5\u03c1\u03c3\u03b7, \u03c0\u03b9\u03b8\u03b1\u03bd\u03cc\u03c4\u03b1\u03c4\u03b1, \u03b4\u03b7\u03bc\u03b9\u03bf\u03c5\u03c1\u03b3\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9 \u03ba\u03b1\u03c4\u03ac \u03c4\u03b1 \u03b1\u03c1\u03c7\u03b9\u03ba\u03ac \u03c3\u03c4\u03ac\u03b4\u03b9\u03b1 \u03c4\u03b7\u03c2 \u03b4\u03b9\u03b1\u03b4\u03b9\u03ba\u03b1\u03c3\u03af\u03b1\u03c2 \u03c0\u03b1\u03c1\u03b1\u03c3\u03ba\u03b5\u03c5\u03ae\u03c2 \u03c4\u03bf\u03c5 mRNA \u03c0\u03bf\u03c5 \u03b8\u03b1 \u03c7\u03c1\u03b7\u03c3\u03b9\u03bc\u03bf\u03c0\u03bf\u03b9\u03b7\u03b8\u03b5\u03af \u03b3\u03b9\u03b1 \u03c4\u03bf \u03b5\u03bc\u03b2\u03cc\u03bb\u03b9\u03bf \u03ae \u03c0\u03c1\u03bf\u03ba\u03cd\u03c0\u03c4\u03bf\u03c5\u03bd \u03b1\u03c1\u03b3\u03cc\u03c4\u03b5\u03c1\u03b1 \u03ba\u03b1\u03c4\u03ac \u03c4\u03b7\u03bd \u03c0\u03b1\u03c1\u03b1\u03c3\u03ba\u03b5\u03c5\u03ae \u03ae \u03b1\u03c0\u03bf\u03b8\u03ae\u03ba\u03b5\u03c5\u03c3\u03b7 \u03c4\u03c9\u03bd \u03b5\u03bc\u03b2\u03bf\u03bb\u03af\u03c9\u03bd, \u03bb\u03cc\u03b3\u03c9 \u03c4\u03b7\u03c2 \u03b5\u03b3\u03b3\u03b5\u03bd\u03bf\u03cd\u03c2 \u03b1\u03c3\u03c4\u03ac\u03b8\u03b5\u03b9\u03b1\u03c2 \u03c4\u03bf\u03c5 RNA. \u0397 \u03c4\u03c1\u03bf\u03c0\u03bf\u03c0\u03bf\u03af\u03b7\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03bd\u03bf\u03c5\u03ba\u03bb\u03b5\u03bf\u03c4\u03b9\u03b4\u03b9\u03ba\u03ae\u03c2 \u03c3\u03cd\u03bd\u03b8\u03b5\u03c3\u03b7\u03c2 \u03c4\u03bf\u03c5 \u03b2\u03b9\u03bf\u03bc\u03bf\u03c1\u03af\u03bf\u03c5, \u03ce\u03c3\u03c4\u03b5 \u03bd\u03b1 \u03c0\u03b5\u03c1\u03b9\u03ad\u03c7\u03b5\u03b9 \u039d1-\u03bc\u03b5\u03b8\u03c5\u03bb\u03c8\u03b5\u03c5\u03b4\u03bf-\u03bf\u03c5\u03c1\u03b9\u03b4\u03af\u03bd\u03b7 \u03b1\u03bd\u03c4\u03af \u03c4\u03b7\u03c2 \u03bf\u03c5\u03c1\u03b9\u03b4\u03af\u03bd\u03b7\u03c2, \u03b5\u03bb\u03b1\u03c7\u03b9\u03c3\u03c4\u03bf\u03c0\u03bf\u03b9\u03b5\u03af \u03b1\u03bb\u03bb\u03ac \u03b4\u03b5\u03bd \u03b1\u03c0\u03bf\u03c4\u03c1\u03ad\u03c0\u03b5\u03b9 \u03c0\u03ac\u03bd\u03c4\u03b1 \u03c4\u03ad\u03c4\u03bf\u03b9\u03b5\u03c2 \u03b1\u03bd\u03b5\u03c0\u03b9\u03b8\u03cd\u03bc\u03b7\u03c4\u03b5\u03c2 \u03b1\u03bd\u03bf\u03c3\u03bf\u03b1\u03c0\u03bf\u03ba\u03c1\u03af\u03c3\u03b5\u03b9\u03c2. \u0395\u03c0\u03af\u03c3\u03b7\u03c2, \u03c0\u03b1\u03c1\u03ac \u03c4\u03b7\u03bd \u03b5\u03bd\u03b8\u03c5\u03bb\u03ac\u03ba\u03c9\u03c3\u03b7 \u03c4\u03bf\u03c5 mRNA \u03c3\u03b5 \u03bb\u03b9\u03c0\u03bf\u03c3\u03c9\u03bc\u03b9\u03b1\u03ba\u03ac \u03bd\u03b1\u03bd\u03bf\u03c3\u03c9\u03bc\u03b1\u03c4\u03af\u03b4\u03b9\u03b1 (LNP), \u03b7 \u03b1\u03c0\u03bf\u03b4\u03cc\u03bc\u03b7\u03c3\u03ae \u03c4\u03bf\u03c5 \u03b4\u03b5\u03bd \u03b1\u03c0\u03bf\u03ba\u03bb\u03b5\u03af\u03b5\u03c4\u03b1\u03b9 \u03bd\u03b1 \u03c3\u03c5\u03bc\u03b2\u03b5\u03af, \u03b9\u03b4\u03b9\u03b1\u03af\u03c4\u03b5\u03c1\u03b1 \u03b1\u03bd \u03b4\u03b5\u03bd \u03b1\u03ba\u03bf\u03bb\u03bf\u03c5\u03b8\u03b7\u03b8\u03bf\u03cd\u03bd \u03c3\u03c9\u03c3\u03c4\u03ac \u03bf\u03b9 \u03bf\u03b4\u03b7\u03b3\u03af\u03b5\u03c2 \u03b1\u03c0\u03bf\u03b8\u03ae\u03ba\u03b5\u03c5\u03c3\u03b7\u03c2, \u03ba\u03b1\u03c4\u03ac\u03c8\u03c5\u03be\u03b7\u03c2 \u03ba\u03b1\u03b9 \u03b1\u03c0\u03cc\u03c8\u03c5\u03be\u03b7\u03c2. \u03a3\u03c5\u03bd\u03b5\u03c0\u03ce\u03c2, \u03bf\u03b9 \u03c0\u03c1\u03b1\u03ba\u03c4\u03b9\u03ba\u03ad\u03c2 \u03c0\u03b1\u03c1\u03b1\u03c3\u03ba\u03b5\u03c5\u03ae\u03c2 \u03b8\u03b1 \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03b1\u03ba\u03bf\u03bb\u03bf\u03c5\u03b8\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9 \u03c3\u03c7\u03bf\u03bb\u03b1\u03c3\u03c4\u03b9\u03ba\u03ac, \u03ba\u03c5\u03c1\u03af\u03c9\u03c2 \u03b3\u03b9\u03b1 \u03c4\u03bf\u03bd \u03ba\u03b1\u03b8\u03b1\u03c1\u03b9\u03c3\u03bc\u03cc \u03c4\u03bf\u03c5 mRNA \u03b1\u03bb\u03bb\u03ac \u03ba\u03b1\u03b9 \u03b3\u03b9\u03b1 \u03c4\u03b7 \u03b4\u03b9\u03b1\u03c3\u03c6\u03ac\u03bb\u03b9\u03c3\u03b7 \u03c0\u03bf\u03b9\u03bf\u03c4\u03b9\u03ba\u03bf\u03cd \u03b5\u03bb\u03ad\u03b3\u03c7\u03bf\u03c5 \u03ba\u03ac\u03b8\u03b5 \u03b4\u03cc\u03c3\u03b7\u03c2 \u03b5\u03bc\u03b2\u03bf\u03bb\u03af\u03bf\u03c5.<\/p>\n\n\n\n
\u0397 \u03ad\u03c1\u03b5\u03c5\u03bd\u03b1 \u03c0\u03bf\u03c5 \u03b4\u03b7\u03bc\u03bf\u03c3\u03b9\u03b5\u03cd\u03b8\u03b7\u03ba\u03b5 \u03c3\u03c4\u03bf \u03c0\u03b5\u03c1\u03b9\u03bf\u03b4\u03b9\u03ba\u03cc Vaccine \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1 \u03c4\u03b7\u03c2 \u03c3\u03c5\u03bd\u03b5\u03c1\u03b3\u03b1\u03c3\u03af\u03b1\u03c2 \u03c4\u03b7\u03c2 \u0391’ \u03a0\u03b1\u03bd\u03b5\u03c0\u03b9\u03c3\u03c4\u03b7\u03bc\u03b9\u03b1\u03ba\u03ae\u03c2 \u039a\u03b1\u03c1\u03b4\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ae\u03c2 \u039a\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae\u03c2 \u03c4\u03bf\u03c5 \u0399\u03c0\u03c0\u03bf\u03ba\u03c1\u03b1\u03c4\u03b5\u03af\u03bf\u03c5 \u039d\u03bf\u03c3\u03bf\u03ba\u03bf\u03bc\u03b5\u03af\u03bf\u03c5 (\u03b4\u03c1 \u0393\u03b5\u03ce\u03c1\u03b3\u03b9\u03bf\u03c2 \u039b\u03ac\u03b6\u03b1\u03c1\u03bf\u03c2 \u03ba\u03b1\u03b9 \u03ba\u03b1\u03b8\u03b7\u03b3\u03b7\u03c4\u03ae\u03c2 \u039a\u03c9\u03bd\u03c3\u03c4\u03b1\u03bd\u03c4\u03af\u03bd\u03bf\u03c2 \u03a4\u03c3\u03b9\u03bf\u03cd\u03c6\u03b7\u03c2) \u03ba\u03b1\u03b9 \u03c4\u03bf\u03c5 \u0395\u03c1\u03b3\u03b1\u03c3\u03c4\u03b7\u03c1\u03af\u03bf\u03c5 \u039c\u03b9\u03ba\u03c1\u03bf\u03b2\u03b9\u03bf\u03bb\u03bf\u03b3\u03af\u03b1\u03c2 \u03c4\u03b7\u03c2 \u0399\u03b1\u03c4\u03c1\u03b9\u03ba\u03ae\u03c2 \u03a3\u03c7\u03bf\u03bb\u03ae\u03c2 \u03c4\u03bf\u03c5 \u03a0\u03b1\u03bd\u03b5\u03c0\u03b9\u03c3\u03c4\u03b7\u03bc\u03af\u03bf\u03c5 \u0391\u03b8\u03b7\u03bd\u03ce\u03bd (\u03b1\u03bd\u03b1\u03c0\u03bb\u03b7\u03c1\u03ce\u03c4\u03c1\u03b9\u03b1 \u03ba\u03b1\u03b8\u03b7\u03b3\u03ae\u03c4\u03c1\u03b9\u03b1 \u039a\u03bb\u03b5\u03b9\u03ce \u0391\u03bd\u03b1\u03c3\u03c4\u03b1\u03c3\u03bf\u03c0\u03bf\u03cd\u03bb\u03bf\u03c5 \u03ba\u03b1\u03b9 \u03ba\u03b1\u03b8\u03b7\u03b3\u03b7\u03c4\u03ae\u03c2 \u0391\u03b8\u03b1\u03bd\u03ac\u03c3\u03b9\u03bf\u03c2 \u03a4\u03c3\u03b1\u03ba\u03c1\u03ae\u03c2). \u03a3\u03c5\u03bc\u03bc\u03b5\u03c4\u03b5\u03af\u03c7\u03b1\u03bd, \u03b5\u03c0\u03af\u03c3\u03b7\u03c2, \u03c4\u03bf Department of Cardiovascular Medicine \u03c4\u03b7\u03c2 Cleveland Clinic \u03c4\u03bf\u03c5 \u039f\u03c7\u03ac\u03b9\u03bf \u03c4\u03c9\u03bd \u0397\u03a0\u0391 (\u03ba\u03b1\u03b8\u03b7\u03b3\u03b7\u03c4\u03ae\u03c2 Allan L. Klein) \u03ba\u03b1\u03b9 \u03c4\u03bf \u0395\u03c1\u03b3\u03b1\u03c3\u03c4\u03ae\u03c1\u03b9\u03bf \u03a6\u03b1\u03c1\u03bc\u03b1\u03ba\u03b5\u03c5\u03c4\u03b9\u03ba\u03ae\u03c2 \u03a4\u03b5\u03c7\u03bd\u03bf\u03bb\u03bf\u03b3\u03af\u03b1\u03c2 \u03c4\u03bf\u03c5 \u03a4\u03bc\u03ae\u03bc\u03b1\u03c4\u03bf\u03c2 \u03a6\u03b1\u03c1\u03bc\u03b1\u03ba\u03b5\u03c5\u03c4\u03b9\u03ba\u03ae\u03c2 \u03c4\u03bf\u03c5 \u03a0\u03b1\u03bd\u03b5\u03c0\u03b9\u03c3\u03c4\u03b7\u03bc\u03af\u03bf\u03c5 \u03a0\u03b1\u03c4\u03c1\u03ce\u03bd (\u03b5\u03c0\u03af\u03ba\u03bf\u03c5\u03c1\u03b7 \u03ba\u03b1\u03b8\u03b7\u03b3\u03ae\u03c4\u03c1\u03b9\u03b1 \u03a3\u03bf\u03c6\u03af\u03b1 \u03a7\u03b1\u03c4\u03b6\u03b7\u03b1\u03bd\u03c4\u03c9\u03bd\u03af\u03bf\u03c5).<\/p>\n\n\n\n
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