\u0393\u03b9\u03b1 \u03c0\u03c1\u03ce\u03c4\u03b7 \u03c6\u03bf\u03c1\u03ac \u03c3\u03c4\u03b7\u03bd \u0395\u03bb\u03bb\u03ac\u03b4\u03b1 \u03c7\u03bf\u03c1\u03b7\u03b3\u03ae\u03b8\u03b7\u03ba\u03b5 \u03c4\u03b7\u03bd \u03c0\u03c1\u03bf\u03b7\u03b3\u03bf\u03cd\u03bc\u03b5\u03bd\u03b7 \u03a0\u03ad\u03bc\u03c0\u03c4\u03b7 \u03b7 \u03b2\u03b5\u03bb\u03bc\u03b1\u03bd\u03ac\u03c3\u03b7 \u03ac\u03bb\u03c6\u03b1 (velmanase alfa) \u03c3\u03b5 \u03b1\u03bd\u03ae\u03bb\u03b9\u03ba\u03bf \u03b1\u03c3\u03b8\u03b5\u03bd\u03ae \u03bc\u03b5 \u03b1-\u039c\u03b1\u03bd\u03bd\u03bf\u03c3\u03af\u03b4\u03c9\u03c3\u03b7. \u0397 \u03c7\u03bf\u03c1\u03ae\u03b3\u03b7\u03c3\u03b7 \u03ad\u03b3\u03b9\u03bd\u03b5 \u03bc\u03b5 \u03b5\u03c0\u03b9\u03c4\u03c5\u03c7\u03af\u03b1 \u03c3\u03c4\u03b7\u03bd \u0391\u0384 \u03a0\u03b1\u03b9\u03b4\u03b9\u03b1\u03c4\u03c1\u03b9\u03ba\u03ae \u039a\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03c3\u03c4\u03bf \u0399\u03c0\u03c0\u03bf\u03ba\u03c1\u03ac\u03c4\u03b5\u03b9\u03bf \u039d\u03bf\u03c3\u03bf\u03ba\u03bf\u03bc\u03b5\u03af\u03bf \u0398\u03b5\u03c3\u03c3\u03b1\u03bb\u03bf\u03bd\u03af\u03ba\u03b7\u03c2, \u03b7 \u03bf\u03c0\u03bf\u03af\u03b1 \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03b5\u03af \u00ab\u039a\u03ad\u03bd\u03c4\u03c1\u03bf \u0391\u03bd\u03b1\u03c6\u03bf\u03c1\u03ac\u03c2\u00bb \u03b3\u03b9\u03b1 \u03c4\u03b9\u03c2 \u03a3\u03c0\u03ac\u03bd\u03b9\u03b5\u03c2 \u03a0\u03b1\u03b8\u03ae\u03c3\u03b5\u03b9\u03c2. <\/p>\n\n\n\n
\u0397 \u03c7\u03bf\u03c1\u03ae\u03b3\u03b7\u03c3\u03b7 \u03ad\u03b3\u03b9\u03bd\u03b5 \u03b4\u03c5\u03bd\u03b1\u03c4\u03ae \u03bc\u03b5\u03c4\u03ac \u03c4\u03b9\u03c2 \u03b5\u03bd\u03ad\u03c1\u03b3\u03b5\u03b9\u03b5\u03c2 \u03c4\u03b7\u03c2 \u03b4\u03b9\u03bf\u03af\u03ba\u03b7\u03c3\u03b7\u03c2 \u03c4\u03bf\u03c5 \u039d\u03bf\u03c3\u03bf\u03ba\u03bf\u03bc\u03b5\u03af\u03bf\u03c5, \u03ce\u03c3\u03c4\u03b5 \u03bd\u03b1 \u03b1\u03c0\u03bf\u03ba\u03c4\u03b7\u03b8\u03b5\u03af \u03b7 \u03c0\u03c1\u03cc\u03c3\u03b2\u03b1\u03c3\u03b7 \u03c3\u03c4\u03b7\u03bd \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 \u03bc\u03ad\u03c3\u03c9 \u03c4\u03bf\u03c5 \u0399\u03a6\u0395\u03a4. \u00ab\u0395\u03af\u03bd\u03b1\u03b9 \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03cc \u03c0\u03bf\u03c5 \u03b7 \u03c0\u03c1\u03bf\u03bc\u03ae\u03b8\u03b5\u03b9\u03b1 \u03c4\u03bf\u03c5 \u03bd\u03ad\u03bf\u03c5 \u03c6\u03b1\u03c1\u03bc\u03ac\u03ba\u03bf\u03c5 \u03b5\u03b3\u03ba\u03c1\u03af\u03b8\u03b7\u03ba\u03b5 \u03b1\u03c0\u03cc \u03c4\u03bf \u03c5\u03c0\u03bf\u03c5\u03c1\u03b3\u03b5\u03af\u03bf \u03a5\u03b3\u03b5\u03af\u03b1\u03c2, \u03ba\u03ac\u03c4\u03b9 \u03c0\u03bf\u03c5 \u03b4\u03b5\u03af\u03c7\u03bd\u03b5\u03b9 \u03c4\u03b7\u03bd \u03b5\u03c5\u03b1\u03b9\u03c3\u03b8\u03b7\u03c3\u03af\u03b1 \u03b3\u03b9\u03b1 \u03c4\u03b1 \u03c3\u03c0\u03ac\u03bd\u03b9\u03b1 \u03bd\u03bf\u03c3\u03ae\u03bc\u03b1\u03c4\u03b1, \u03b1\u03ba\u03cc\u03bc\u03b1 \u03ba\u03b1\u03b9 \u03b5\u03bd \u03bc\u03ad\u03c3\u03c9 \u03c0\u03b1\u03bd\u03b4\u03b7\u03bc\u03af\u03b1\u03c2\u00bb, \u03b1\u03bd\u03b1\u03c6\u03ad\u03c1\u03b5\u03b9 \u03c3\u03b5 \u03b1\u03bd\u03b1\u03ba\u03bf\u03af\u03bd\u03c9\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03c4\u03bf \u03bd\u03bf\u03c3\u03bf\u03ba\u03bf\u03bc\u03b5\u03af\u03bf. \u0391\u03c0\u03cc \u03c4\u03b7\u03bd \u03c0\u03bb\u03b5\u03c5\u03c1\u03ac \u03c4\u03bf\u03c5, \u03bf \u03c5\u03c0\u03bf\u03c5\u03c1\u03b3\u03cc\u03c2 \u03a5\u03b3\u03b5\u03af\u03b1\u03c2 \u0392\u03b1\u03c3\u03af\u03bb\u03b7\u03c2 \u039a\u03b9\u03ba\u03af\u03bb\u03b9\u03b1\u03c2 \u03c3\u03b5 \u03b4\u03ae\u03bb\u03c9\u03c3\u03b7 \u03c4\u03bf\u03c5, \u03b1\u03c6\u03bf\u03cd \u03b1\u03bd\u03b1\u03c6\u03ad\u03c1\u03b5\u03b9 \u03c0\u03c9\u03c2 \u03b7 \u03b1-\u039c\u03b1\u03bd\u03bd\u03bf\u03c3\u03af\u03b4\u03c9\u03c3\u03b7 \u03b5\u03af\u03bd\u03b1\u03b9 \u03ad\u03bd\u03b1 \u03c3\u03c0\u03ac\u03bd\u03b9\u03bf \u03ba\u03bb\u03b7\u03c1\u03bf\u03bd\u03bf\u03bc\u03b9\u03ba\u03cc \u03bd\u03cc\u03c3\u03b7\u03bc\u03b1, \u03bc\u03b5 \u03c4\u03bf \u03bf\u03c0\u03bf\u03af\u03bf \u03c5\u03c0\u03bf\u03bb\u03bf\u03b3\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03cc\u03c4\u03b9 \u03b3\u03b5\u03bd\u03bd\u03b9\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9 \u03ad\u03bd\u03b1 \u03c3\u03c4\u03b1 500.000 \u03c0\u03b1\u03b9\u03b4\u03b9\u03ac \u03ba\u03b1\u03b9 \u03bc\u03ad\u03c7\u03c1\u03b9 \u03c0\u03c1\u03cc\u03c4\u03b9\u03bd\u03bf\u03c2 \u03b4\u03b5\u03bd \u03c5\u03c0\u03ae\u03c1\u03c7\u03b5 \u03ba\u03b1\u03bc\u03af\u03b1 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1, \u03c3\u03b7\u03bc\u03b5\u03b9\u03ce\u03bd\u03b5\u03b9: \u00ab\u039d\u03b9\u03ce\u03b8\u03c9 \u03b9\u03b4\u03b9\u03b1\u03af\u03c4\u03b5\u03c1\u03b7 \u03b9\u03ba\u03b1\u03bd\u03bf\u03c0\u03bf\u03af\u03b7\u03c3\u03b7 \u03cc\u03c4\u03b1\u03bd \u03b7 \u03b5\u03c0\u03b9\u03c3\u03c4\u03ae\u03bc\u03b7 \u03bc\u03ac\u03c2 \u03b4\u03af\u03bd\u03b5\u03b9 \u03bb\u03cd\u03c3\u03b5\u03b9\u03c2, \u03b3\u03b9\u03b1 \u03bd\u03b1 \u03bc\u03c0\u03bf\u03c1\u03bf\u03cd\u03bc\u03b5 \u03bd\u03b1 \u03b4\u03af\u03bd\u03bf\u03c5\u03bc\u03b5 \u03c0\u03c1\u03cc\u03c3\u03b2\u03b1\u03c3\u03b7 \u03c3\u03c4\u03b7 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1, \u03c0\u03c1\u03bf\u03c3\u03c6\u03ad\u03c1\u03bf\u03bd\u03c4\u03b1\u03c2 \u03ad\u03bd\u03b1 \u03ba\u03b1\u03bb\u03cd\u03c4\u03b5\u03c1\u03bf \u03bc\u03ad\u03bb\u03bb\u03bf\u03bd \u03c3\u03c4\u03bf\u03c5\u03c2 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03ba\u03b1\u03b9 \u03c4\u03b9\u03c2 \u03bf\u03b9\u03ba\u03bf\u03b3\u03ad\u03bd\u03b5\u03b9\u03ad\u03c2 \u03c4\u03bf\u03c5\u03c2. <\/p>\n\n\n\n
\u0397 \u03b5\u03c5\u03b1\u03b9\u03c3\u03b8\u03b7\u03c3\u03af\u03b1 \u03c4\u03bf\u03c5 \u03c5\u03c0\u03bf\u03c5\u03c1\u03b3\u03b5\u03af\u03bf\u03c5 \u03a5\u03b3\u03b5\u03af\u03b1\u03c2 \u03b3\u03b9\u03b1 \u03c4\u03b1 \u03c3\u03c0\u03ac\u03bd\u03b9\u03b1 \u03bd\u03bf\u03c3\u03ae\u03bc\u03b1\u03c4\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b4\u03b5\u03b4\u03bf\u03bc\u03ad\u03bd\u03b7 \u03ba\u03b1\u03b9 \u03ba\u03ac\u03bd\u03bf\u03c5\u03bc\u03b5 \u03cc,\u03c4\u03b9 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03bd\u03b8\u03c1\u03c9\u03c0\u03af\u03bd\u03c9\u03c2 \u03b4\u03c5\u03bd\u03b1\u03c4\u03cc\u03bd \u03b3\u03b9\u03b1 \u03c4\u03bf\u03c5\u03c2 \u03c3\u03c5\u03bc\u03c0\u03bf\u03bb\u03af\u03c4\u03b5\u03c2 \u03bc\u03b1\u03c2, \u03b1\u03ba\u03cc\u03bc\u03b1 \u03ba\u03b1\u03b9 \u03b5\u03bd \u03bc\u03ad\u03c3\u03c9 \u03c0\u03b1\u03bd\u03b4\u03b7\u03bc\u03af\u03b1\u03c2, \u03c3\u03cd\u03bc\u03c6\u03c9\u03bd\u03b1 \u03bc\u03b5 \u03c4\u03b9\u03c2 \u03ba\u03b1\u03c4\u03b5\u03c5\u03b8\u03cd\u03bd\u03c3\u03b5\u03b9\u03c2 \u03c0\u03bf\u03c5 \u03bc\u03b1\u03c2 \u03b4\u03af\u03bd\u03bf\u03c5\u03bd \u03bf\u03b9 \u03b5\u03c0\u03b9\u03c3\u03c4\u03ae\u03bc\u03bf\u03bd\u03b5\u03c2 \u03ba\u03b1\u03b9 \u03bf\u03b9 \u03b8\u03b5\u03c1\u03ac\u03c0\u03bf\u03bd\u03c4\u03b5\u03c2 \u03b9\u03b1\u03c4\u03c1\u03bf\u03af. \u03a3\u03c5\u03b3\u03c7\u03b1\u03c1\u03b7\u03c4\u03ae\u03c1\u03b9\u03b1 \u03c3\u03c4\u03b7\u03bd \u03bf\u03bc\u03ac\u03b4\u03b1 \u03c4\u03b7\u03c2 \u0391\u0384 \u03a0\u03b1\u03b9\u03b4\u03b9\u03b1\u03c4\u03c1\u03b9\u03ba\u03ae\u03c2 \u039a\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae\u03c2 \u03c3\u03c4\u03bf \u0399\u03c0\u03c0\u03bf\u03ba\u03c1\u03ac\u03c4\u03b5\u03b9\u03bf \u039d\u03bf\u03c3\u03bf\u03ba\u03bf\u03bc\u03b5\u03af\u03bf \u0398\u03b5\u03c3\u03c3\u03b1\u03bb\u03bf\u03bd\u03af\u03ba\u03b7\u03c2\u00bb. \u0397 \u039c\u03b1\u03bd\u03bd\u03bf\u03c3\u03af\u03b4\u03c9\u03c3\u03b7 \u03c4\u03cd\u03c0\u03bf\u03c5 \u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03ad\u03bd\u03b1 \u03c3\u03c0\u03ac\u03bd\u03b9\u03bf \u03ba\u03bb\u03b7\u03c1\u03bf\u03bd\u03bf\u03bc\u03b9\u03ba\u03cc \u03bb\u03c5\u03c3\u03bf\u03c3\u03c9\u03bc\u03b9\u03b1\u03ba\u03cc \u03bd\u03cc\u03c3\u03b7\u03bc\u03b1 \u03bc\u03b5 \u03c4\u03bf \u03bf\u03c0\u03bf\u03af\u03bf \u03c5\u03c0\u03bf\u03bb\u03bf\u03b3\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03cc\u03c4\u03b9 \u03b3\u03b5\u03bd\u03bd\u03b9\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9 \u03ad\u03bd\u03b1 \u03c3\u03c4\u03b1 500.000 \u03c0\u03b1\u03b9\u03b4\u03b9\u03ac. \u039f\u03c6\u03b5\u03af\u03bb\u03b5\u03c4\u03b1\u03b9 \u03c3\u03b5 \u03b1\u03bd\u03b5\u03c0\u03ac\u03c1\u03ba\u03b5\u03b9\u03b1 \u03bc\u03b9\u03b1\u03c2 \u03b5\u03bd\u03b6\u03c5\u03bc\u03b9\u03ba\u03ae\u03c2 \u03c0\u03c1\u03c9\u03c4\u03b5\u0390\u03bd\u03b7\u03c2, \u03c4\u03b7\u03c2 \u03b1-\u039c\u03b1\u03bd\u03bd\u03bf\u03c3\u03b9\u03b4\u03ce\u03c3\u03b7\u03c2 (MANB) \u03bc\u03b5 \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1 \u03c3\u03c5\u03c3\u03c3\u03ce\u03c1\u03b5\u03c5\u03c3\u03b7 \u03bf\u03bb\u03b9\u03b3\u03bf\u03c3\u03b1\u03ba\u03c7\u03b1\u03c1\u03b9\u03c4\u03ce\u03bd (\u03ba\u03c5\u03c1\u03af\u03c9\u03c2 \u03bc\u03b1\u03bd\u03bd\u03cc\u03b6\u03b7\u03c2) \u03c3\u03b5 \u03b4\u03b9\u03ac\u03c6\u03bf\u03c1\u03b1 \u03cc\u03c1\u03b3\u03b1\u03bd\u03b1. <\/p>\n\n\n\n
\u03a0\u03c1\u03bf\u03ba\u03b1\u03bb\u03b5\u03af\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03bc\u03b5\u03c4\u03ac\u03bb\u03bb\u03b1\u03be\u03b7 \u03c3\u03c4\u03bf \u03b3\u03bf\u03bd\u03af\u03b4\u03b9\u03bf \u03c4\u03b7\u03c2 MANB (MAN2B1), \u03c4\u03bf \u03bf\u03c0\u03bf\u03af\u03bf \u03ad\u03c7\u03b5\u03b9 \u03b5\u03bd\u03c4\u03bf\u03c0\u03b9\u03c3\u03c4\u03b5\u03af \u03c3\u03c4\u03bf \u03c7\u03c1\u03c9\u03bc\u03cc\u03c3\u03c9\u03bc\u03b1 19p13.2-q12. \u038c\u03c0\u03c9\u03c2 \u03c3\u03c5\u03bd\u03b5\u03c7\u03af\u03b6\u03b5\u03b9 \u03c3\u03c4\u03b7\u03bd \u03b1\u03bd\u03b1\u03ba\u03bf\u03af\u03bd\u03c9\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03c4\u03bf \u0393\u03b5\u03bd\u03b9\u03ba\u03cc \u039d\u03bf\u03c3\u03bf\u03ba\u03bf\u03bc\u03b5\u03af\u03bf \u0398\u03b5\u03c3\u03c3\u03b1\u03bb\u03bf\u03bd\u03af\u03ba\u03b7\u03c2 “\u0399\u03c0\u03c0\u03bf\u03ba\u03c1\u03ac\u03c4\u03b5\u03b9\u03bf”, \u00ab\u03c4\u03bf \u03bd\u03cc\u03c3\u03b7\u03bc\u03b1 \u03c7\u03b1\u03c1\u03b1\u03ba\u03c4\u03b7\u03c1\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c0\u03c1\u03bf\u03bf\u03b4\u03b5\u03c5\u03c4\u03b9\u03ba\u03ae \u03b5\u03bc\u03c6\u03ac\u03bd\u03b9\u03c3\u03b7 \u03b1\u03c4\u03b1\u03be\u03af\u03b1\u03c2, \u03bc\u03c5\u03ca\u03ba\u03ae\u03c2 \u03b1\u03b4\u03c5\u03bd\u03b1\u03bc\u03af\u03b1\u03c2, \u03ba\u03b1\u03b8\u03c5\u03c3\u03c4\u03ad\u03c1\u03b7\u03c3\u03b7 \u03bb\u03cc\u03b3\u03bf\u03c5, \u03bd\u03b5\u03c5\u03c1\u03bf\u03b1\u03b9\u03c3\u03b8\u03b7\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03ae\u03c2 \u03b2\u03b1\u03c1\u03b7\u03ba\u03bf\u0390\u03b1\u03c2, \u03bd\u03bf\u03b7\u03c4\u03b9\u03ba\u03ae\u03c2 \u03c5\u03c3\u03c4\u03ad\u03c1\u03b7\u03c3\u03b7\u03c2, \u03b1\u03bd\u03bf\u03c3\u03bf\u03b1\u03bd\u03b5\u03c0\u03ac\u03c1\u03ba\u03b5\u03b9\u03b1\u03c2, \u03c3\u03ba\u03b5\u03bb\u03b5\u03c4\u03b9\u03ba\u03ad\u03c2 \u03b4\u03c5\u03c3\u03bc\u03bf\u03c1\u03c6\u03af\u03b5\u03c2 \u03ba\u03b1\u03b9 \u03b4\u03c5\u03c3\u03bc\u03bf\u03c1\u03c6\u03af\u03b5\u03c2 \u03c0\u03c1\u03bf\u03c3\u03ce\u03c0\u03bf\u03c5, \u03bc\u03ad\u03c4\u03c1\u03b9\u03b1-\u03c3\u03bf\u03b2\u03b1\u03c1\u03ae \u03c0\u03bf\u03bb\u03bb\u03b1\u03c0\u03bb\u03ae \u03b4\u03c5\u03c3\u03cc\u03c3\u03c4\u03c9\u03c3\u03b7 \u03ba\u03b1\u03c4\u03b1\u03c3\u03c4\u03c1\u03bf\u03c6\u03b9\u03ba\u03ae \u03c0\u03bf\u03bb\u03c5\u03b1\u03c1\u03b8\u03c1\u03bf\u03c0\u03ac\u03b8\u03b5\u03b9\u03b1 \u03bc\u03b5 \u03c4\u03b5\u03bb\u03b9\u03ba\u03ae \u03ba\u03b1\u03c4\u03ac\u03bb\u03b7\u03be\u03b7 \u03c4\u03b9\u03c2 \u03c3\u03bf\u03b2\u03b1\u03c1\u03ad\u03c2 \u03ba\u03b9\u03bd\u03b7\u03c4\u03b9\u03ba\u03ad\u03c2 \u03ba\u03b1\u03b9 \u03b5\u03ba\u03c4\u03b5\u03bb\u03b5\u03c3\u03c4\u03b9\u03ba\u03ad\u03c2 \u03b4\u03b9\u03b1\u03c4\u03b1\u03c1\u03b1\u03c7\u03ad\u03c2 \u03c4\u03c9\u03bd \u03b1\u03c3\u03b8\u03b5\u03bd\u03ce\u03bd\u00bb. <\/p>\n\n\n\n
\u00ab\u0397 \u03b1-\u039c\u03b1\u03bd\u03bd\u03bf\u03c3\u03af\u03b4\u03c9\u03c3\u03b7 \u03b4\u03b5\u03bd \u03ad\u03c7\u03b5\u03b9 \u03c6\u03c5\u03bb\u03b5\u03c4\u03b9\u03ba\u03ae \u03c0\u03c1\u03bf\u03c4\u03af\u03bc\u03b7\u03c3\u03b7. \u039f\u03b9 \u03c0\u03b5\u03c1\u03b9\u03c0\u03c4\u03ce\u03c3\u03b5\u03b9\u03c2 \u03c0\u03bf\u03c5 \u03ad\u03c7\u03bf\u03c5\u03bd \u03b1\u03bd\u03b1\u03c6\u03b5\u03c1\u03b8\u03b5\u03af \u03c0\u03c1\u03bf\u03ad\u03c1\u03c7\u03bf\u03bd\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03bf\u03bb\u03cc\u03ba\u03bb\u03b7\u03c1\u03bf \u03c4\u03bf\u03bd \u03ba\u03cc\u03c3\u03bc\u03bf \u03ba\u03b1\u03b9 \u03b7 \u03c0\u03c1\u03ce\u03c4\u03b7 \u03c0\u03b5\u03c1\u03af\u03c0\u03c4\u03c9\u03c3\u03b7 \u03b1\u03c3\u03b8\u03b5\u03bd\u03bf\u03cd\u03c2 \u03b4\u03b7\u03bc\u03bf\u03c3\u03b9\u03b5\u03cd\u03b8\u03b7\u03ba\u03b5 \u03c4\u03bf 1967 (Ockerman)\u00bb \u03b1\u03bd\u03b1\u03c6\u03ad\u03c1\u03b5\u03b9 \u03b5\u03c0\u03af\u03c3\u03b7\u03c2 \u03c4\u03bf \u039d\u03bf\u03c3\u03bf\u03ba\u03bf\u03bc\u03b5\u03af\u03bf \u03ba\u03b1\u03b9 \u03c3\u03b7\u03bc\u03b5\u03b9\u03ce\u03bd\u03b5\u03b9: \u00ab\u0397 velmanase alfa \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03b5\u03af \u03c4\u03b7\u03bd \u03c0\u03c1\u03ce\u03c4\u03b7 \u03b5\u03b3\u03ba\u03b5\u03ba\u03c1\u03b9\u03bc\u03ad\u03bd\u03b7 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 \u03b3\u03b9\u03b1 \u03c4\u03b7\u03bd \u03b1- \u039c\u03b1\u03bd\u03bd\u03bf\u03c3\u03af\u03b4\u03c9\u03c3\u03b7, \u03b7 \u03bf\u03c0\u03bf\u03af\u03b1 \u03ad\u03bb\u03b1\u03b2\u03b5 \u03ad\u03b3\u03ba\u03c1\u03b9\u03c3\u03b7 \u03b1\u03c0\u03cc \u03c4\u03bf\u03bd \u0395\u03c5\u03c1\u03c9\u03c0\u03b1\u03ca\u03ba\u03cc \u039f\u03c1\u03b3\u03b1\u03bd\u03b9\u03c3\u03bc\u03cc \u03a6\u03b1\u03c1\u03bc\u03ac\u03ba\u03c9\u03bd \u03c4\u03bf \u039c\u03ac\u03c1\u03c4\u03b9\u03bf \u03c4\u03bf\u03c5 2018. \u03a0\u03c1\u03cc\u03ba\u03b5\u03b9\u03c4\u03b1\u03b9 \u03b3\u03b9\u03b1 \u03bc\u03b1\u03ba\u03c1\u03bf\u03c7\u03c1\u03cc\u03bd\u03b9\u03b1 \u03b1\u03b3\u03c9\u03b3\u03ae \u03b5\u03bd\u03b6\u03c5\u03bc\u03b9\u03ba\u03ae\u03c2 \u03c5\u03c0\u03bf\u03ba\u03b1\u03c4\u03ac\u03c3\u03c4\u03b1\u03c3\u03b7\u03c2 \u03b3\u03b9\u03b1 \u03c4\u03b7 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 \u03c4\u03c9\u03bd \u03bc\u03b7 \u03bd\u03b5\u03c5\u03c1\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ce\u03bd \u03b5\u03ba\u03b4\u03b7\u03bb\u03ce\u03c3\u03b5\u03c9\u03bd \u03c3\u03c4\u03bf\u03c5\u03c2 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 (\u03c0\u03b1\u03b9\u03b4\u03b9\u03ac, \u03b5\u03c6\u03ae\u03b2\u03bf\u03c5\u03c2 \u03ba\u03b1\u03b9 \u03b5\u03bd\u03ae\u03bb\u03b9\u03ba\u03b5\u03c2), \u03bc\u03b5 \u03ae\u03c0\u03b9\u03b1 \u03ad\u03c9\u03c2 \u03bc\u03ad\u03c4\u03c1\u03b9\u03b1 \u03bc\u03bf\u03c1\u03c6\u03ae \u03c4\u03b7\u03c2 \u03b1-\u039c\u03b1\u03bd\u03bd\u03bf\u03c3\u03af\u03b4\u03c9\u03c3\u03b7\u03c2. <\/p>\n\n\n\n
\u0397 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 \u03b1\u03bd\u03c4\u03b9\u03ba\u03b1\u03b8\u03b9\u03c3\u03c4\u03ac \u03c4\u03bf \u03ad\u03bd\u03b6\u03c5\u03bc\u03bf \u03c0\u03bf\u03c5 \u03bb\u03b5\u03af\u03c0\u03b5\u03b9 \u03c3\u03c4\u03bf\u03bd \u03bf\u03c1\u03b3\u03b1\u03bd\u03b9\u03c3\u03bc\u03cc \u03ba\u03b1\u03b9 \u03b2\u03bf\u03b7\u03b8\u03ac \u03c3\u03c4\u03b7\u03bd \u03b1\u03c0\u03bf\u03ba\u03b1\u03c4\u03ac\u03c3\u03c4\u03b1\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03ba\u03c5\u03c4\u03c4\u03b1\u03c1\u03b9\u03ba\u03ae\u03c2 \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b1\u03c2. \u0397 \u03b1\u03c3\u03c6\u03ac\u03bb\u03b5\u03b9\u03b1 \u03ba\u03b1\u03b9 \u03b7 \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03b5\u03c3\u03bc\u03b1\u03c4\u03b9\u03ba\u03cc\u03c4\u03b7\u03c4\u03b1 \u03c4\u03bf\u03c5 \u03c6\u03b1\u03c1\u03bc\u03ac\u03ba\u03bf\u03c5 \u03ad\u03c7\u03bf\u03c5\u03bd \u03b5\u03c1\u03b5\u03c5\u03bd\u03b7\u03b8\u03b5\u03af \u03c3\u03b5 5 \u03b2\u03b1\u03c3\u03b9\u03ba\u03ad\u03c2 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b5\u03c2 \u03c3\u03c4\u03b9\u03c2 \u03bf\u03c0\u03bf\u03af\u03b5\u03c2 \u03ad\u03bb\u03b1\u03b2\u03b1\u03bd \u03bc\u03ad\u03c1\u03bf\u03c2 33 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03b7\u03bb\u03b9\u03ba\u03af\u03b1\u03c2 \u03b1\u03c0\u03cc 6 \u03ad\u03c9\u03c2 35 \u03b5\u03c4\u03ce\u03bd. <\/p>\n\n\n\n
\u0397 \u03c7\u03bf\u03c1\u03ae\u03b3\u03b7\u03c3\u03b7 \u03b3\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03b5\u03bd\u03b4\u03bf\u03c6\u03bb\u03b5\u03b2\u03af\u03c9\u03c2 \u03bc\u03af\u03b1 \u03c6\u03bf\u03c1\u03ac \u03c4\u03b7\u03bd \u03b5\u03b2\u03b4\u03bf\u03bc\u03ac\u03b4\u03b1\u00bb \u03a5\u03c0\u03b5\u03cd\u03b8\u03c5\u03bd\u03bf\u03b9 \u03b3\u03b9\u03b1\u03c4\u03c1\u03bf\u03af \u03b3\u03b9\u03b1 \u03c4\u03b7 \u03c7\u03bf\u03c1\u03ae\u03b3\u03b7\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 \u03ae\u03c4\u03b1\u03bd \u03bf \u0394\u03b7\u03bc\u03ae\u03c4\u03c1\u03b9\u03bf\u03c2 \u0396\u03b1\u03c6\u03b5\u03b9\u03c1\u03af\u03bf\u03c5, \u03ba\u03b1\u03b8\u03b7\u03b3\u03b7\u03c4\u03ae\u03c2 \u03a0\u03b1\u03b9\u03b4\u03b9\u03b1\u03c4\u03c1\u03b9\u03ba\u03ae\u03c2 \u039d\u03b5\u03c5\u03c1\u03bf\u03bb\u03bf\u03b3\u03af\u03b1\u03c2-\u0391\u03bd\u03b1\u03c0\u03c4\u03c5\u03be\u03b9\u03bf\u03bb\u03bf\u03b3\u03af\u03b1\u03c2 \u0391\u03a0\u0398, \u03ba\u03b1\u03b9 \u03b7 \u0395\u03c5\u03b8\u03c5\u03bc\u03af\u03b1 \u0392\u03b1\u03c1\u03b3\u03b9\u03ac\u03bc\u03b7, \u03b1\u03bd\u03b1\u03c0\u03bb\u03b7\u03c1\u03ce\u03c4\u03c1\u03b9\u03b1 \u03ba\u03b1\u03b8\u03b7\u03b3\u03ae\u03c4\u03c1\u03b9\u03b1 \u03a0\u03b1\u03b9\u03b4\u03b9\u03b1\u03c4\u03c1\u03b9\u03ba\u03ae\u03c2 \u0391\u03a0\u0398, \u03b7 \u03bf\u03c0\u03bf\u03af\u03bf\u03b9 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b5\u03c0\u03b9\u03ba\u03b5\u03c6\u03b1\u03bb\u03ae\u03c2 \u03bf\u03bc\u03ac\u03b4\u03b1\u03c2 \u03b9\u03b1\u03c4\u03c1\u03bf\u03bd\u03bf\u03c3\u03b7\u03bb\u03b5\u03c5\u03c4\u03b9\u03ba\u03bf\u03cd \u03c0\u03c1\u03bf\u03c3\u03c9\u03c0\u03b9\u03ba\u03bf\u03cd.<\/p>\n\n\n\n
\u0391\u03a0\u0395 \u039c\u03a0\u0395<\/em><\/p>\n","protected":false},"excerpt":{"rendered":" \u0393\u03b9\u03b1 \u03c0\u03c1\u03ce\u03c4\u03b7 \u03c6\u03bf\u03c1\u03ac \u03c3\u03c4\u03b7\u03bd \u0395\u03bb\u03bb\u03ac\u03b4\u03b1 \u03c7\u03bf\u03c1\u03b7\u03b3\u03ae\u03b8\u03b7\u03ba\u03b5 \u03c4\u03b7\u03bd \u03c0\u03c1\u03bf\u03b7\u03b3\u03bf\u03cd\u03bc\u03b5\u03bd\u03b7 \u03a0\u03ad\u03bc\u03c0\u03c4\u03b7 \u03b7 \u03b2\u03b5\u03bb\u03bc\u03b1\u03bd\u03ac\u03c3\u03b7 \u03ac\u03bb\u03c6\u03b1 (velmanase alfa) \u03c3\u03b5 \u03b1\u03bd\u03ae\u03bb\u03b9\u03ba\u03bf \u03b1\u03c3\u03b8\u03b5\u03bd\u03ae \u03bc\u03b5 \u03b1-\u039c\u03b1\u03bd\u03bd\u03bf\u03c3\u03af\u03b4\u03c9\u03c3\u03b7. \u0397 \u03c7\u03bf\u03c1\u03ae\u03b3\u03b7\u03c3\u03b7 \u03ad\u03b3\u03b9\u03bd\u03b5 \u03bc\u03b5 \u03b5\u03c0\u03b9\u03c4\u03c5\u03c7\u03af\u03b1 \u03c3\u03c4\u03b7\u03bd \u0391\u0384 \u03a0\u03b1\u03b9\u03b4\u03b9\u03b1\u03c4\u03c1\u03b9\u03ba\u03ae \u039a\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03c3\u03c4\u03bf \u0399\u03c0\u03c0\u03bf\u03ba\u03c1\u03ac\u03c4\u03b5\u03b9\u03bf \u039d\u03bf\u03c3\u03bf\u03ba\u03bf\u03bc\u03b5\u03af\u03bf \u0398\u03b5\u03c3\u03c3\u03b1\u03bb\u03bf\u03bd\u03af\u03ba\u03b7\u03c2, \u03b7 \u03bf\u03c0\u03bf\u03af\u03b1 \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03b5\u03af \u00ab\u039a\u03ad\u03bd\u03c4\u03c1\u03bf \u0391\u03bd\u03b1\u03c6\u03bf\u03c1\u03ac\u03c2\u00bb \u03b3\u03b9\u03b1 \u03c4\u03b9\u03c2 \u03a3\u03c0\u03ac\u03bd\u03b9\u03b5\u03c2 \u03a0\u03b1\u03b8\u03ae\u03c3\u03b5\u03b9\u03c2. \u0397 \u03c7\u03bf\u03c1\u03ae\u03b3\u03b7\u03c3\u03b7 \u03ad\u03b3\u03b9\u03bd\u03b5 \u03b4\u03c5\u03bd\u03b1\u03c4\u03ae \u03bc\u03b5\u03c4\u03ac \u03c4\u03b9\u03c2 \u03b5\u03bd\u03ad\u03c1\u03b3\u03b5\u03b9\u03b5\u03c2 \u03c4\u03b7\u03c2 \u03b4\u03b9\u03bf\u03af\u03ba\u03b7\u03c3\u03b7\u03c2…<\/p>\n","protected":false},"author":1,"featured_media":3041,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_bbp_topic_count":0,"_bbp_reply_count":0,"_bbp_total_topic_count":0,"_bbp_total_reply_count":0,"_bbp_voice_count":0,"_bbp_anonymous_reply_count":0,"_bbp_topic_count_hidden":0,"_bbp_reply_count_hidden":0,"_bbp_forum_subforum_count":0,"footnotes":""},"categories":[19],"tags":[],"class_list":["post-3039","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-health"],"_links":{"self":[{"href":"https:\/\/portal.fonisalaminas.gr\/index.php\/wp-json\/wp\/v2\/posts\/3039","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/portal.fonisalaminas.gr\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/portal.fonisalaminas.gr\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/portal.fonisalaminas.gr\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/portal.fonisalaminas.gr\/index.php\/wp-json\/wp\/v2\/comments?post=3039"}],"version-history":[{"count":1,"href":"https:\/\/portal.fonisalaminas.gr\/index.php\/wp-json\/wp\/v2\/posts\/3039\/revisions"}],"predecessor-version":[{"id":3040,"href":"https:\/\/portal.fonisalaminas.gr\/index.php\/wp-json\/wp\/v2\/posts\/3039\/revisions\/3040"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/portal.fonisalaminas.gr\/index.php\/wp-json\/wp\/v2\/media\/3041"}],"wp:attachment":[{"href":"https:\/\/portal.fonisalaminas.gr\/index.php\/wp-json\/wp\/v2\/media?parent=3039"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/portal.fonisalaminas.gr\/index.php\/wp-json\/wp\/v2\/categories?post=3039"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/portal.fonisalaminas.gr\/index.php\/wp-json\/wp\/v2\/tags?post=3039"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}